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Caution: Avoid if allergic to plants in the Asteraceae family, as cross-reactivity may occur

When GPX4 is removed from mice models, adults lost body weight and died within 2 weeks due to mitochondrial damage, decreased electron transport chain activity (Yoo et al., 2012)
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(+)-CLA attenuates APAP-induced cytotoxicity through activating the Keap1Nrf2 pathway It has been revealed that Keap1Nrf2 plays a central role in protecting hepatocellular carcinoma (HCC) cells against ferroptosis 10