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Additionally, FOXA1-driven upregulation of IGF-1R transcription further exemplifies the reversible transcriptional plasticity utilized by DTP cells to temporarily adapt to drug exposure (Wang et al., 2020)

This outcome might be linked to the triggering of F-actin formation, as indicated by FITC-phalloidin staining

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10 For each regimen, akathisia was generally mild or moderate in severity and reported early in treatment