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In accordance with this, it has been estimated that the steady-state concentration of superoxide in the mitochondrial matrix is 5- to 10- fold higher than in the cytosol (Fernandez-Checa and Kaplowitz, 2005
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The cochleas reported histopathological lesions in all groups were scored as follows: no change = zero, mild change = 1, mild to moderate change = 2, moderate change = 3, moderate to severe change = 4, severe change = 5
