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Annu Rev Pathol: Mech Dis

ketoconazole), and protease inhibitors (e.g., ritonavir), may result in an increase in codeine plasma concentrations , with subsequently greater metabolism by cytochrome CYP2D6, resulting in greater morphine levels, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression, particularly when an inhibitor is added after a stable dose of acetaminophen and codeine phosphate tablets is achieved [see WARNINGS]

Endocrine disruptors and prostate cancer

Build a context-of-use argument for each NAM tied to a specific decision, the way the FDA now expects