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(2019) 143:AB132

The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)

Its included in our formula to help maintain comfort and tissue homeostasis in the gut and connective tissues as part of a daily wellness routine

Lautt WW

[30] This property allows the convenient preparation of cobalamin analogs with different substituents, via nucleophilic attack on alkyl halides and vinyl halides