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Description

Nat Commun 13 , 5184 (2022)

Nutrafol Blend: Tributyrin, Marigold Extract (Flower) (25% Lutein, 5% Zeaxanthin), Bamboo Extract (Leaf) (70% Silica), Bacillus subtilis DE111 (1 Billion CFU), Spermidine

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

For the experiment, 56 healthy male adult rats were randomly selected and were divided into seven equal groups (n = 8) and treated as: NC as normal control group (normal saline 10 ml/kg body weight/day, orally), high lipid diet group (HLD, 10 ml/kg body weight/day, orally which equates to 600 ml/60 kg of humans respectively), monosodium glutamate group (MSG, 600 mg/kg body weight/day, orally which equates to 3.6 g/60 kg of humans respectively), HLD + MSG group (HM, 10 ml/kg body weight/day, orally + 600 mg/kg body weight/day, orally), HM + low dose of EECGL (EECGLL, 200 mg/kg body weight/day, orally which equates to 1.2 g/60 kg of humans respectively), HM + medium dose of EECGL (EECGLM, 400 mg/kg body weight/day, orally which equates to 2.4 g/60 kg of humans respectively), HM + high dose of EECGL (EECGLH, 600 mg/kg body weight/day, orally which equates to 3.6 g/60 kg of humans respectively)