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Pei R, Mah E, Leonard SW, Traber MG, Bruno RS (2015) -Tocopherol supplementation reduces 5-nitro--tocopherol accumulation by decreasing -tocopherol in young adult smokers

In vivo, emodin and tetrahydropalmatine synergistically reduces colon cancer (HT-29) tumor size, increasing F4/80 expression, decreasing IL-6 and TGF- levels, promoting tumor oxidation, and down-regulating p53 and STAT3 protein expression

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This adaptive resistance underscores the complexity of ferroptosis regulation in lung tumors and highlights the need for context-specific approaches to restore ferroptotic vulnerability (80, 81)

Adenovirus generation A pENTR-gene-mCherry entry clone was generated for the gene of interest, and the pAd/CMV/V5-DEST Gateway kit (Invitrogen, #V49320) was then used to perform the LR recombination reaction to create a pAd/CMV/V5-gene-mCherry adenoviral expression clone
