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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Simonsen E., Lund L.C., Ernst M.T., et al

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Functional imaging studies show that GLP-1R agonists blunt neural responses to reward cues in the ventral tegmental area and nucleus accumbens, and retrospective and early prospective data link their use to reduced intake of alcohol and nicotine

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Pharmacokinetic assessment is crucial to understand how GLP-1 receptor agonists are absorbed, distributed, metabolized, and excreted, guiding optimal dosing, and ensuring therapeutic efficacy