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Likewise, five clinical trials in T2DM patients (SURPASS 15) have shown that tirzepatide at 515 mg per week reduces both HbA1c (1.242.58%) and body weight (5.411.7 kg) by amounts unprecedented for a single agent (Del Prato et al

Hunger modulates the responses to gustatory stimuli of single neurons in the Caudolateral orbitofrontal cortex of the macaque monkey
Journal of Pharmacy Policy Practice

Semaglutide, by contrast, shows significant deceleration after 6-8 months, with monthly weight loss dropping to 1-2 pounds as patients approach the 12-15% plateau

Susan Peirce Thompson, Ph.D, is the New York Times bestselling author of Bright Line Eating, The Official Bright Line Eating Cookbook, and Rezoom