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When that peace lifts, it can feel like losing something fundamental

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This finding adds a layer of complexity to how sex differences are considered and indicates that comparisons should ideally be stratified by pre- vs postmenopausal age, to assess the extent of activational vs organizational contribution to the potentially detected sex difference

A modest increase in resting heart rate was also observed at higher doses

So I think there are so many things that you can learn from this, and of course it can also inform when you look at what's actually mediating the effect and probably something around inflammation is important