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This effect may reduce cravings for certain addictive behaviors such as overeating or alcohol consumption, but it does not mean they eliminate motivation or emotional experiences

Purpose-built for physicians Off-label semaglutide, tirzepatide lower HbA1c and body weight in type 1 diabetes Key takeaways: Adults with type 1 diabetes had significant declines in body weight at 1 year of off-label semaglutide and tirzepatide use

95% CI, 1.21-1.53) when compared with SGLT2 inhibitors, which was driven by an increase in the risk for GI motility-related outcomes, the researchers wrote

[10] [11] Fatigue and mood disturbances may reduce motivation for physical activity and lead to emotional eating patterns

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