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We demonstrated that in GLUTag cells, a high glucose level with L-glutamine stimulates GLP-1 secretion through a synergistic effect rather than cAMP amplification, and that a high glucose level potentiates L-glutamine-Gs activation in GLP-1 secretion
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The mean percentage change in body weight from baseline to 68 weeks was 14.9% in the semaglutide group versus 2.4% in the placebo group
A little refresher on GLP-1 What is a GLP-1 agonist
