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Finally, the certainty of the outcomes was categorized into four classes based on evidence classification criteria: Class I (convincing evidence), Class II (highly suggestive evidence), Class III (suggestive evidence), Class IV (weak evidence), and NS (non-significant) 58,61

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Eur J Heart Fail 22:19841986 Mizuno Y, Harada E, Nakagawa H, Morikawa Y, Shono M, Kugimiya F, Yoshimura M, Yasue H (2017) The diabetic heart utilizes ketone bodies as an energy source

Resuming your normal schedule after a missed dose is safer and maintains more predictable receptor occupancy
The dedicated cardiovascular outcomes trial, SURPASS-CVOT, is ongoing and will provide definitive long-term data
