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The first steps in treatment usually involve rehydrating the patient, managing their pain, providing antibiotics, and often using a nasogastric tube (a tube from the nose to the stomach) to relieve pressure in the stomach

However, because they also slow digestion and promote feelings of fullness, many people who take them experience weight loss as a secondary effect

391 GLP-1 and GLP-1 analogs exert their effects on food intake and body weight through a myriad of neural substrates, encompassing several hypothalamic nuclei (including the arcuate nucleus of the hypothalamus, periventricular hypothalamus, and lateral hypothalamic area), hindbrain nuclei (such as the parabrachial nucleus and medial nucleus tractus solitarius), the ventral subregion of the hippocampus (vHP), and nuclei embedded within the mesolimbic reward circuitry (including the ventral tegmental area, VTA, and nucleus accumbens, NAc)

What Happens When I Lose The Weight I Want

Many patients begin to notice appetite reduction within the first 12 weeks