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Brains were later sectioned on Leica CM3000 cryostat, and 1 mm punches (Integra Miltex Biopsy Punch) of the hypothalamus, hippocampus and hindbrain were collected

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Moreover, dual GLP-1 and Gcg receptor agonist, dual GLP-1/GIP receptor agonist and GLP-1/GIP/Gcg receptor triagonist have also been successfully applied in the treatment of AD models