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Description
Frontiers Pharmacol

This activates protein kinase A (PKA), which phosphorylates the sulfonylurea receptor-1 (SUR1) subunit of the K + /ATPase channel, leading to early closure of this channel and an amplified physiological Ca 2+ influx via voltage-gated calcium channels

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Most include herbal stimulants and lack any scientific backing
Both parts of the ADC (targeting region and payload) can be modified to target different types of tumors using different cancer drugs
