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Risk ratios (RR) for the renal outcome estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons

This includes trials of drug combinations such as Novo Nordisks CagriSema that combines semaglutide with investigational drug cagrilintide to improve efficacy

Child Obes 16(3):174-191

A health care provider should help patients determine if these medications are appropriate for them

[DOI] [PubMed] [Google Scholar] [155].Nauck M, Weinstock RS, Umpierrez GE, Guerci B, Skrivanek Z, Milicevic Z, Efficacy and safety of dulaglutide versus sitagliptin after 52 weeks in type 2 diabetes in a randomized controlled trial (AWARD-5), Diabetes care, 37 (2014) 21492158