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9 Patients with T2DM receive exenatide by subcutaneous injection, and circulating exenatide produces a blood glucose-lowering effect since it directly activates the GLP-1R

Participants had two band adjustments over first 6 months and one band adjustment over the 6 month follow-up period (Supplementary Table 16)

Pathological processes such as oligodendroglial insulin signaling defects, glial inflammation, mitochondrial stress, and impaired proteostasis overlap with pathways modulated by GLP-1R stimulation