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Last reviewed: June 21, 2026 Last updated: June 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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By conducting KEGG metabolic pathway enrichment analysis on the differential metabolites of each group, it can be observed that a high-fat diet affects the biosynthesis of phenylalanine, tyrosine, and tryptophan, taurine and hypotaurine metabolism, phenylalanine metabolism, and arachidonic acid metabolism in mice

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