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Description
For type 2 diabetes , NICE NG28 recommends continuing GLP-1 treatment only if there is adequate response, defined as HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at 6 months

They started low and slowly increased the dose over time

For perspective on where this lands against the field (placebo-adjusted weight loss): Type 2 diabetes TRANSCEND-T2D-1 (n = 537, 40 weeks) Published simultaneously in The Lancet
Dr Bimisa Augustin (05:54) Okay, so that's a famous question too about, you know, muscle wasting

While brand names like Ozempic and Wegovy are well-known, compounded versions of semaglutide are also available
