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Researchers have also tested higher doses of oral semaglutide, 25 mg and 50 mg, for weight loss in adults without diabetes who have: A body mass index (BMI) of 30 or higher A BMI of 27 or higher with at least one weight-related health condition, such as high blood pressure Although not FDA-approved for weight management, Rybelsus also helps in weight loss (as an additional benefit) in people with type 2 diabetes, especially when diet and exercise alone do not provide sufficient control

Many patients taking tirzepatide are also prescribed other medications that can affect sexual function, including: Antidepressants (particularly SSRIs) Some antihypertensive medications (especially thiazide diuretics and beta-blockers) Hormonal contraceptives Important contraceptive information: Tirzepatide can reduce oral contraceptive exposure after initiation and dose increases

Key lifestyle investments during treatment include developing a sustainable eating pattern that does not rely on appetite suppression, building strength training habits that preserve and build lean mass, addressing emotional eating patterns through therapy or structured programs, establishing sleep hygiene that supports metabolic health, and managing stress through sustainable practices