how were glp 1 drugs discovered Discovery of GLP-1–Based for the Treatment of Obesity A new NIH-funded study found
Description
At day 6 after the first infusion, the semaglutide-treated and GLP-1MK-801-treated mice were crossed-over in terms of treatment and administered with another single infusion of either GLP-1MK-801 (0.22 nmol, 2 l) and semaglutide (0.22 nmol, 2 l), respectively, while vehicle-treated mice received vehicle treatment once again
Some data suggests that higher doses of tirzepatide may be associated with a higher risk of gastrointestinal issues compared to semaglutide
doi: 10.2337/db14-0849
doi: 10.2337/diab.42.11.1678
ICAM-1: intracellular adhesion molecule-1
