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Description
In people with DKD, the once-weekly GLP-1 receptor agonist dulaglutide increased mGFR (37), although semaglutide appeared to initially reduce eGFR (15)

Tirzepatide exerts its therapeutic effects through dual agonism of two key incretin receptors: the GIPR and the GLP-1R

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Treatment and Prevention of Herpes Labialis

Results announced in October 2025 demonstrated orforglipron's superiority on both HbA1c and weight endpoints, positioning it as a more effective second-line oral agent than existing oral diabetes medications
