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Description
The EMA European Public Assessment Reports (EPARs) for Wegovy, Ozempic, and Mounjaro provide further detail on the GI safety profiles of these approved agents and represent the most authoritative class-level evidence currently available

Any history of alcohol-related health problems , including liver disease, pancreatitis, gastritis, or previous attempts to reduce drinking Changes in drinking patterns since starting GLP-1 medication, whether increased or decreased consumption, or altered tolerance to alcohol Gastrointestinal symptoms and whether alcohol worsens nausea, vomiting, or other side effects Concerns about alcohol use disorder : If you're finding it difficult to control your drinking, your GP can arrange referral to specialist NHS alcohol services Your GP should provide personalised advice based on your individual circumstances, including other medications, comorbidities, and treatment goals

GLP-1 medications reduce appetite and slow gastric emptying, which often creates a significant calorie deficit in the early weeks of treatment

The improvement in HbA1c particularly noteworthy , as this biomarker is the most commonly used for diagnosing diabetes and prediabetes

The average age of GLP-1 medication users in the UK is 44 years , with people aged 40-59 making up more than half of users (53.5%)
