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A 56-week trial included 422 patients with BMI30 kg/m 2 or BMI27 kg/m 2 with dyslipidemia and/or hypertension (non-diabetic)

The median follow-up time was 1.05 years

As mentioned before, obesity is associated with a state of chronic, low-grade inflammation characterized by abnormal cytokine production and the activation of inflammatory signaling pathways in adipose tissue [76]

Specifically, it has been established that 50% to 70% of insulin secretion in response to oral glucose administration is due to the incretin effect [1]

No illnesses have been reported, but the company has removed the product from shelves in all eight states where it operates and is providing full refunds to customers