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Further dose increases of 2.5 mg increments can be made at 4-week intervals, up to a maximum of 15 mg once weekly , based on glycaemic response and tolerability

Weight-management use+ Mounjaro is used for weight management in adults with obesity, or overweight adults with weight-related health problems, alongside diet and activity

There is no required washout period, but starting low helps assess individual tolerability of the new compounds unique receptor profile

The best characterized activators include temperatures greater than 43 C, low pH, capsaicin, and allyl isothiocyanate [80]

Seizures are not listed as a recognised adverse effect in the Summary of Product Characteristics