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Research is revealing a bad news, good news situation when it comes to how GLP-1 medications affect pregnancy

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Most see measurable results within a few weeks, with maximum benefits building over several months

in a case of extreme IR (Rabson-Mendenhall syndrome) ( Combination therapy with a GLP-1 RA and a SGLT2i has been reported to involve additional benefits in the management of T2DM compared with monotherapy through different mechanisms ( via an improvement in insulin sensitivity ( Funding This study was supported by Centros de Investigacin Biomdica en Red (CIBER) of Instituto de Salud Carlos III (ISCIII) (CB06/03/0018) and research grants from the ISCIII (PI18/01160), and co-financed by the European Regional Development Fund (ERDF)